Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome

OBJECTIVE: Primary Sjögren syndrome (pSS) is characterized by T and B cell infiltration of exocrine glands. The cysteine protease cathepsin S (CatS) is crucially involved in MHCII processing and T cell stimulation, and elevated levels have been found in patients with RA, psoriasis and pSS. However,...

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Опубликовано в: :Arthritis Res Ther
Главные авторы: Hargreaves, Patrick, Daoudlarian, Douglas, Theron, Michel, Kolb, Fabrice A., Manchester Young, Marianne, Reis, Bernhard, Tiaden, Andre, Bannert, Bettina, Kyburz, Diego, Manigold, Tobias
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637481/
https://ncbi.nlm.nih.gov/pubmed/31319889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1955-2
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