Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production

Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity. However, insights into the role of CFH in B cell biology are limited. Here, we dem...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Kiss, Máté G., Ozsvár-Kozma, Mária, Porsch, Florentina, Göderle, Laura, Papac-Miličević, Nikolina, Bartolini-Gritti, Barbara, Tsiantoulas, Dimitrios, Pickering, Matthew C., Binder, Christoph J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637296/
https://ncbi.nlm.nih.gov/pubmed/31354740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01607
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