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Innate sensing of oxidation-specific epitopes in health and disease

Ageing, infections and inflammation result in oxidative stress that can irreversibly damage cellular structures. The oxidative damage of lipids in membranes or lipoproteins is one of these deleterious consequences that not only alters lipid function but also leads to the formation of neo-self epitop...

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Foilsithe in:Nat Rev Immunol
Main Authors: Binder, Christoph J., Papac-Milicevic, Nikolina, Witztum, Joseph L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097710/
https://ncbi.nlm.nih.gov/pubmed/27346802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri.2016.63
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