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Complement Factor H Modulates Splenic B Cell Development and Limits Autoantibody Production
Complement factor H (CFH) has a pivotal role in regulating alternative complement activation through its ability to inhibit the cleavage of the central complement component C3, which links innate and humoral immunity. However, insights into the role of CFH in B cell biology are limited. Here, we dem...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6637296/ https://ncbi.nlm.nih.gov/pubmed/31354740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01607 |
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