Poly-γ-Glutamic Acid Complexed With Alum Induces Cross-Protective Immunity of Pandemic H1N1 Vaccine

The use of a good vaccine adjuvant may induce a higher immunogenicity profile of vaccine antigens. Here, we developed a new adjuvant by combining poly-γ-glutamic acid (γ-PGA) with alum (PGA/Alum) and investigated its ability to enhance the immunogenicity and the cross-reactive efficacy of pandemic H...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Nguyen, Quyen Thi, Kwak, Chaewon, Lee, Wang Sik, Kim, Jaemoo, Jeong, Jinyoung, Sung, Moon Hee, Yang, Jihyun, Poo, Haryoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637289/
https://ncbi.nlm.nih.gov/pubmed/31354739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01604
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