Poly-γ-glutamic acid/chitosan nanogel greatly enhances the efficacy and heterosubtypic cross-reactivity of H1N1 pandemic influenza vaccine

In 2009, the global outbreak of an influenza pandemic emphasized the need for an effective vaccine adjuvant. In this study, we examined the efficacy of poly-γ-glutamic acid/chitosan (PC) nanogel as an adjuvant for the influenza vaccine. PC nanogel significantly enhanced antigen-specific cross-presen...

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Publicat a:Sci Rep
Autors principals: Yang, Jihyun, Shim, Sang-Mu, Nguyen, Thi Quyen, Kim, Eun-Ha, Kim, Kwang, Lim, Yong Taik, Sung, Moon-Hee, Webby, Richard, Poo, Haryoung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359587/
https://ncbi.nlm.nih.gov/pubmed/28322289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44839
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