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Poly-γ-glutamic acid/chitosan nanogel greatly enhances the efficacy and heterosubtypic cross-reactivity of H1N1 pandemic influenza vaccine

In 2009, the global outbreak of an influenza pandemic emphasized the need for an effective vaccine adjuvant. In this study, we examined the efficacy of poly-γ-glutamic acid/chitosan (PC) nanogel as an adjuvant for the influenza vaccine. PC nanogel significantly enhanced antigen-specific cross-presen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Jihyun, Shim, Sang-Mu, Nguyen, Thi Quyen, Kim, Eun-Ha, Kim, Kwang, Lim, Yong Taik, Sung, Moon-Hee, Webby, Richard, Poo, Haryoung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359587/
https://ncbi.nlm.nih.gov/pubmed/28322289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44839
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