Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

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Bibliografiske detaljer
Udgivet i:J Adv Res
Main Authors: Cebrián, Rubén, Rodríguez-Cabezas, M. Elena, Martín-Escolano, Rubén, Rubiño, Susana, Garrido-Barros, María, Montalbán-López, Manuel, Rosales, María José, Sánchez-Moreno, Manuel, Valdivia, Eva, Martínez-Bueno, Manuel, Marín, Clotilde, Gálvez, Julio, Maqueda, Mercedes
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637140/
https://ncbi.nlm.nih.gov/pubmed/31360546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.06.003
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