Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Adv Res
Autori principali: Cebrián, Rubén, Rodríguez-Cabezas, M. Elena, Martín-Escolano, Rubén, Rubiño, Susana, Garrido-Barros, María, Montalbán-López, Manuel, Rosales, María José, Sánchez-Moreno, Manuel, Valdivia, Eva, Martínez-Bueno, Manuel, Marín, Clotilde, Gálvez, Julio, Maqueda, Mercedes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637140/
https://ncbi.nlm.nih.gov/pubmed/31360546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.06.003
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