Preclinical studies of toxicity and safety of the AS-48 bacteriocin

The in vitro antimicrobial potency of the bacteriocin AS-48 is well documented, but its clinical application requires investigation, as its toxicity could be different in in vitro (haemolytic and antibacterial activity in blood and cytotoxicity towards normal human cell lines) and in vivo (e.g. mice...

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Veröffentlicht in:J Adv Res
Hauptverfasser: Cebrián, Rubén, Rodríguez-Cabezas, M. Elena, Martín-Escolano, Rubén, Rubiño, Susana, Garrido-Barros, María, Montalbán-López, Manuel, Rosales, María José, Sánchez-Moreno, Manuel, Valdivia, Eva, Martínez-Bueno, Manuel, Marín, Clotilde, Gálvez, Julio, Maqueda, Mercedes
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637140/
https://ncbi.nlm.nih.gov/pubmed/31360546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2019.06.003
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