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Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes
Lysine 2-hydroxyisobutyrylation (Khib) has recently been shown to be an evolutionarily conserved histone mark. Here, we report that CobB serves as a lysine de-2-hydroxyisobutyrylation enzyme that regulates glycolysis and cell growth in prokaryotes. We identified the specific binding of CobB to Khib...
Shranjeno v:
| izdano v: | Sci Adv |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Association for the Advancement of Science
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6636992/ https://ncbi.nlm.nih.gov/pubmed/31328167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw6703 |
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