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Characterization of CobB kinetics and inhibition by nicotinamide

Lysine acetylation has emerged as a global protein regulation system in all domains of life. Sirtuins, or Sir2-like enzymes, are a family of histone deacetylases characterized by their employing NAD(+) as a co-substrate. Sirtuins can deacetylate several acetylated proteins, but a consensus substrate...

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Vydáno v:PLoS One
Hlavní autoři: Gallego-Jara, Julia, Écija Conesa, Ana, de Diego Puente, Teresa, Lozano Terol, Gema, Cánovas Díaz, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734772/
https://ncbi.nlm.nih.gov/pubmed/29253849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189689
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