Protein lysine de-2-hydroxyisobutyrylation by CobB in prokaryotes

Lysine 2-hydroxyisobutyrylation (Khib) has recently been shown to be an evolutionarily conserved histone mark. Here, we report that CobB serves as a lysine de-2-hydroxyisobutyrylation enzyme that regulates glycolysis and cell growth in prokaryotes. We identified the specific binding of CobB to Khib...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Dong, Hanyang, Zhai, Guijin, Chen, Cong, Bai, Xue, Tian, Shanshan, Hu, Deqing, Fan, Enguo, Zhang, Kai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2019
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636992/
https://ncbi.nlm.nih.gov/pubmed/31328167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw6703
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