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Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive

Emerging evidence indicates the role of amino acid metabolism in sleep regulation. Here we demonstrate sleep-promoting effects of dietary threonine (SPET) in Drosophila. Dietary threonine markedly increased daily sleep amount and decreased the latency to sleep onset in a dose-dependent manner. High...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Ki, Yoonhee, Lim, Chunghun
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636906/
https://ncbi.nlm.nih.gov/pubmed/31313987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40593
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