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Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila

Kohlschutter-Tönz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. Mutations at the Rogdi locus have been linked to development of KTS, yet the underlying mechanisms remain elusive. Here we demonstrate that a Drosophila homolog o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Minjong, Jang, Donghoon, Yoo, Eunseok, Oh, Yangkyun, Sonn, Jun Young, Lee, Jongbin, Ki, Yoonhee, Son, Hyo Jin, Hwang, Onyou, Lee, Changwook, Lim, Chunghun, Choe, Joonho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595912/
https://ncbi.nlm.nih.gov/pubmed/28900300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11941-3
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