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Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive

Emerging evidence indicates the role of amino acid metabolism in sleep regulation. Here we demonstrate sleep-promoting effects of dietary threonine (SPET) in Drosophila. Dietary threonine markedly increased daily sleep amount and decreased the latency to sleep onset in a dose-dependent manner. High...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ki, Yoonhee, Lim, Chunghun
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636906/
https://ncbi.nlm.nih.gov/pubmed/31313987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40593
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