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De novo computational RNA modeling into cryoEM maps of large ribonucleoprotein complexes

Increasingly, cryo-electron microscopy (cryoEM) is used to determine the structures of RNA-protein assemblies, but nearly all maps determined with this method have biologically important regions where the local resolution does not permit RNA coordinate tracing. To address these omissions, we present...

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Publicat a:Nat Methods
Autors principals: Kappel, Kalli, Liu, Shiheng, Larsen, Kevin P., Skiniotis, Georgios, Puglisi, Elisabetta Viani, Puglisi, Joseph D., Zhou, Z. Hong, Zhao, Rui, Das, Rhiju
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636682/
https://ncbi.nlm.nih.gov/pubmed/30377372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41592-018-0172-2
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