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GemSpot: A Pipeline for Robust Modeling of Ligands into CryoEM Maps

Producing an accurate atomic model of biomolecule-ligand interactions from maps generated by cryo-electron microscopy (cryoEM) often presents challenges inherent to the methodology and the dynamic nature of ligand binding. Here we present GemSpot, an automated pipeline of computational chemistry met...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Robertson, Michael J., van Zundert, Gydo C. P., Borrelli, Kenneth, Skiniotis, Georgios
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7272260/
https://ncbi.nlm.nih.gov/pubmed/32413291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.04.018
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