Knockout of Dual-Specificity Protein Phosphatase 5 Protects Against Hypertension-Induced Renal Injury

Dual-specificity protein phosphatase 5 (DUSP5) is a member of the tyrosine-threonine phosphatase family with the ability to dephosphorylate and inactivate extracellular signal-related kinase (ERK). The present study investigates whether knockout (KO) of Dusp5 improves renal hemodynamics and protects...

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Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Zhang, Chao, He, Xiaochen, Murphy, Sydney R., Zhang, Huawei, Wang, Shaoxun, Ge, Ying, Gao, Wenjun, Williams, Jan M., Geurts, Aron M., Roman, Richard J., Fan, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
Schlagworte:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6636243/
https://ncbi.nlm.nih.gov/pubmed/31118214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258954
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