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DMOG, a Prolyl Hydroxylase Inhibitor, Increases Hemoglobin Levels without Exacerbating Hypertension and Renal Injury in Salt-Sensitive Hypertensive Rats

Prolyl hydroxylase (PHD) inhibitors are being developed as alternatives to recombinant human erythropoietin (rHuEPO) for the treatment of anemia in patients with chronic kidney disease (CKD). However, the effects of PHD inhibitors and rHuEPO on blood pressure and CKD in animal models susceptible to...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Kato, Sota, Takahashi, Teisuke, Miyata, Noriyuki, Roman, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978707/
https://ncbi.nlm.nih.gov/pubmed/31801803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.262782
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