Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase

BACKGROUND: The health-promoting and disease-limiting abilities of resveratrol, a natural polyphenol, has led to considerable interest in understanding the mechanisms of its therapeutic actions. The polyphenolic rings of resveratrol enable it to react with and detoxify otherwise injurious oxidants....

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Circulation
Autori principali: Prysyazhna, Oleksandra, Wolhuter, Kathryn, Switzer, Christopher, Santos, Celio, Yang, Xiaoping, Lynham, Steven, Shah, Ajay M., Eaton, Philip, Burgoyne, Joseph R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2019
Soggetti:
Original Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635045/
https://ncbi.nlm.nih.gov/pubmed/31116951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.037398
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