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Novel latonduine derived proligands and their copper(II) complexes show cytotoxicity in the nanomolar range in human colon adenocarcinoma cells and in vitro cancer selectivity

Four Schiff bases derived from 7-hydrazin-yl-5,8-dihydroindolo[2,3-d][2]benzazepin-(6H)-one and its bromo-substituted analogue (HL(1)–HL(4)) and four copper(II) complexes 1–4 have been synthesised and fully characterised by standard spectroscopic methods ((1)H and (13)C NMR, UV–vis), ESI mass spectr...

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Detalhes bibliográficos
Publicado no:Dalton Trans
Main Authors: Bacher, Felix, Wittmann, Christopher, Nové, Márta, Spengler, Gabriella, Marć, Małgorzata A., Enyedy, Eva A., Darvasiova, Denisa, Rapta, Peter, Reiner, Thomas, Arion, Vladimir B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635014/
https://ncbi.nlm.nih.gov/pubmed/31125040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9dt01238a
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