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Targeting NMNAT1 to Axons and Synapses Transforms Its Neuroprotective Potency In Vivo
Axon and synapse degeneration are common components of many neurodegenerative diseases, and their rescue is essential for effective neuroprotection. The chimeric Wallerian degeneration slow protein (Wld(S)) protects axons dose dependently, but its mechanism is still elusive. We recently showed that...
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| Udgivet i: | J Neurosci |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6634738/ https://ncbi.nlm.nih.gov/pubmed/20926655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1189-10.2010 |
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