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Non-Nuclear Wld(S) Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

Axon degeneration contributes widely to neurodegenerative disease but its regulation is poorly understood. The Wallerian degeneration slow (Wld(S)) protein protects axons dose-dependently in many circumstances but is paradoxically abundant in nuclei. To test the hypothesis that Wld(S) acts within nu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Beirowski, Bogdan, Babetto, Elisabetta, Gilley, Jon, Mazzola, Francesca, Conforti, Laura, Janeckova, Lucie, Magni, Giulio, Ribchester, Richard R., Coleman, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665162/
https://ncbi.nlm.nih.gov/pubmed/19158292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3814-08.2009
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