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Non-Nuclear Wld(S) Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

Axon degeneration contributes widely to neurodegenerative disease but its regulation is poorly understood. The Wallerian degeneration slow (Wld(S)) protein protects axons dose-dependently in many circumstances but is paradoxically abundant in nuclei. To test the hypothesis that Wld(S) acts within nu...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Beirowski, Bogdan, Babetto, Elisabetta, Gilley, Jon, Mazzola, Francesca, Conforti, Laura, Janeckova, Lucie, Magni, Giulio, Ribchester, Richard R., Coleman, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665162/
https://ncbi.nlm.nih.gov/pubmed/19158292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3814-08.2009
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