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Pathogenic Lysosomal Depletion in Parkinson's Disease
Mounting evidence suggests a role for autophagy dysregulation in Parkinson's disease (PD). The bulk degradation of cytoplasmic proteins (including α-synuclein) and organelles (such as mitochondria) is mediated by macroautophagy, which involves the sequestration of cytosolic components into auto...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6633458/ https://ncbi.nlm.nih.gov/pubmed/20844148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1920-10.2010 |
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