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Pathogenic Lysosomal Depletion in Parkinson's Disease

Mounting evidence suggests a role for autophagy dysregulation in Parkinson's disease (PD). The bulk degradation of cytoplasmic proteins (including α-synuclein) and organelles (such as mitochondria) is mediated by macroautophagy, which involves the sequestration of cytosolic components into auto...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Dehay, Benjamin, Bové, Jordi, Rodríguez-Muela, Natalia, Perier, Celine, Recasens, Ariadna, Boya, Patricia, Vila, Miquel
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633458/
https://ncbi.nlm.nih.gov/pubmed/20844148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1920-10.2010
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