Disruption of Peripheral Circadian Timekeeping in a Mouse Model of Huntington's Disease and Its Restoration by Temporally Scheduled Feeding

Behavioral circadian rhythms disintegrate progressively in the R6/2 mouse model of Huntington's disease (HD), recapitulating the sleep–wake disturbance seen in HD patients. Here we show that disturbances in circadian pacemaking are not restricted to the brain, but also encompass peripheral meta...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Maywood, Elizabeth S., Fraenkel, Eloise, McAllister, Catherine J., Wood, Nigel, Reddy, Akhilesh B., Hastings, Michael H., Morton, A. Jennifer
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
Sujets:
Brief Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633357/
https://ncbi.nlm.nih.gov/pubmed/20668203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1694-10.2010
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires