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Adaptation to Experimental Jet-Lag in R6/2 Mice despite Circadian Dysrhythmia

The R6/2 transgenic mouse model of Huntington’s disease (HD) shows a disintegration of circadian rhythms that can be delayed by pharmacological and non-pharmacological means. Since the molecular machinery underlying the circadian clocks is intact, albeit progressively dysfunctional, we wondered if l...

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Autori principali: Wood, Nigel I., McAllister, Catherine J., Cuesta, Marc, Aungier, Juliet, Fraenkel, Eloise, Morton, A. Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3563662/
https://ncbi.nlm.nih.gov/pubmed/23390510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055036
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