Disintegration of the Sleep-Wake Cycle and Circadian Timing in Huntington's Disease

Sleep disturbances in neurological disorders have a devastating impact on patient and carer alike. However, their pathological origin is unknown. Here we show that patients with Huntington's disease (HD) have disrupted night-day activity patterns. This disruption was mirrored in a transgenic mo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Morton, A. Jennifer, Wood, Nigel I., Hastings, Michael H., Hurelbrink, Carrie, Barker, Roger A., Maywood, Elizabeth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725210/
https://ncbi.nlm.nih.gov/pubmed/15634777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3842-04.2005
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