In the Adult Hippocampus, Chronic Nerve Growth Factor Deprivation Shifts GABAergic Signaling from the Hyperpolarizing to the Depolarizing Direction

GABA, the main inhibitory transmitter in adulthood, early in postnatal development exerts a depolarizing and excitatory action. This effect, which results from a high intracellular chloride concentration ([Cl(−)](i)), promotes neuronal growth and synaptogenesis. During the second postnatal week, the...

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Publié dans:J Neurosci
Auteurs principaux: Lagostena, Laura, Rosato-Siri, Marcelo, D'Onofrio, Mara, Brandi, Rossella, Arisi, Ivan, Capsoni, Simona, Franzot, Jessica, Cattaneo, Antonino, Cherubini, Enrico
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2010
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633100/
https://ncbi.nlm.nih.gov/pubmed/20089897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3326-09.2010
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