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Dynamic Changes from Depolarizing to Hyperpolarizing GABAergic Actions during Giant Depolarizing Potentials in the Neonatal Rat Hippocampus

During development, GABA exerts depolarizing action on immature neurons and, acting in synergy with glutamate, drives giant depolarizing potentials (GDPs) in the hippocampal network. Yet, blockade of the GABA(A) receptors transforms GDPs to epileptiform discharges suggesting dual, both excitatory an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Khalilov, Ilgam, Minlebaev, Marat, Mukhtarov, Marat, Khazipov, Roustem
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795198/
https://ncbi.nlm.nih.gov/pubmed/26377455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1922-15.2015
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