Involvement of a Subpopulation of Neuronal M(4) Muscarinic Acetylcholine Receptors in the Antipsychotic-like Effects of the M(1)/M(4) Preferring Muscarinic Receptor Agonist Xanomeline

Disturbances in central dopaminergic neurotransmission are believed to be centrally involved in the pathogenesis of schizophrenia. Central dopaminergic and cholinergic systems interact and the cholinergic muscarinic agonist xanomeline has shown antipsychotic effects in clinical studies. Preclinical...

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Foilsithe in:J Neurosci
Main Authors: Dencker, Ditte, Wörtwein, Gitta, Weikop, Pia, Jeon, Jongrye, Thomsen, Morgane, Sager, Thomas N., Mørk, Arne, Woldbye, David P. D., Wess, Jürgen, Fink-Jensen, Anders
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2011
Ábhair:
Brief Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632952/
https://ncbi.nlm.nih.gov/pubmed/21508215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0370-11.2011
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