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Relation between DNA ionization potentials, single base substitutions and pathogenic variants
BACKGROUND: It is nowadays clear that single base substitutions that occur in the human genome, of which some lead to pathogenic conditions, are non-random and influenced by their flanking nucleobase sequences. However, despite recent progress, the understanding of these "non-local" effect...
Gardado en:
| Publicado en: | BMC Genomics |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6631442/ https://ncbi.nlm.nih.gov/pubmed/31307386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5867-y |
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