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Prediction and interpretation of deleterious coding variants in terms of protein structural stability
The classification of human genetic variants into deleterious and neutral is a challenging issue, whose complexity is rooted in the large variety of biophysical mechanisms that can be responsible for disease conditions. For non-synonymous mutations in structured proteins, one of these is the protein...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5852127/ https://ncbi.nlm.nih.gov/pubmed/29540703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22531-2 |
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