In silico Designed Ebola Virus T-Cell Multi-Epitope DNA Vaccine Constructions Are Immunogenic in Mice

Background: The lack of effective vaccines against Ebola virus initiates a search for new approaches to overcoming this problem. The aim of the study was to design artificial polyepitope T-cell immunogens—candidate DNA vaccines against Ebola virus and to evaluate their capacity to induce a specific...

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Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Bazhan, Sergei I., Antonets, Denis V., Karpenko, Larisa I., Oreshkova, Svetlana F., Kaplina, Olga N., Starostina, Ekaterina V., Dudko, Sergei G., Fedotova, Sofia A., Ilyichev, Alexander A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630745/
https://ncbi.nlm.nih.gov/pubmed/30934980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7020034
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