Design and Evaluation of Optimized Artificial HIV-1 Poly-T Cell-Epitope Immunogens

A successful HIV vaccine in addition to induction of antibody responses should elicit effective T cell responses. Here we described possible strategies for rational design of T-cell vaccine capable to induce high levels of both CD4+ and CD8+ T- cell responses. We developed artificial HIV-1 polyepito...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Reguzova, Alena, Antonets, Denis, Karpenko, Larisa, Ilyichev, Alexander, Maksyutov, Rinat, Bazhan, Sergei
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364888/
https://ncbi.nlm.nih.gov/pubmed/25786238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116412
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