Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope

The construction of artificial proteins using conservative B-cell and T-cell epitopes is believed to be a promising approach for a vaccine design against diverse viral infections. This article describes the development of an artificial HIV-1 immunogen using a polyepitope immunogen design strategy. W...

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Pubblicato in:Vaccines (Basel)
Autori principali: Rudometov, Andrey P., Chikaev, Anton N., Rudometova, Nadezhda B., Antonets, Denis V., Lomzov, Alexander A., Kaplina, Olga N., Ilyichev, Alexander A., Karpenko, Larisa I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789618/
https://ncbi.nlm.nih.gov/pubmed/31390770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines7030083
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