Loading...
Recombinant production of ESAT-6 antigen in thermoinducible Escherichia coli: the role of culture scale and temperature on metabolic response, expression of chaperones, and architecture of inclusion bodies
The heat-inducible expression system has been widely used to produce recombinant proteins in Escherichia coli. However, the rise in temperature affects cell growth, activates the bacterial Heat-Shock Response (HSR), and promotes the formation of insoluble protein aggregates known as inclusion bodies...
Saved in:
| Published in: | Cell Stress Chaperones |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Netherlands
2019
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629757/ https://ncbi.nlm.nih.gov/pubmed/31165436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-019-01006-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|