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Acute and chronic hypoxia differentially predispose lungs for metastases

Oscillations in oxygen levels affect malignant cell growth, survival, and metastasis, but also somatic cell behaviour. In this work, we studied the effect of the differential expression of the two primary hypoxia inducible transcription factor isoforms, HIF-1α and HIF-2α, and pulmonary hypoxia to in...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Reiterer, Moritz, Colaço, Renato, Emrouznejad, Pardis, Jensen, Anders, Rundqvist, Helene, Johnson, Randall S., Branco, Cristina
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629695/
https://ncbi.nlm.nih.gov/pubmed/31308473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46763-y
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