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Acute and chronic hypoxia differentially predispose lungs for metastases

Oscillations in oxygen levels affect malignant cell growth, survival, and metastasis, but also somatic cell behaviour. In this work, we studied the effect of the differential expression of the two primary hypoxia inducible transcription factor isoforms, HIF-1α and HIF-2α, and pulmonary hypoxia to in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Reiterer, Moritz, Colaço, Renato, Emrouznejad, Pardis, Jensen, Anders, Rundqvist, Helene, Johnson, Randall S., Branco, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629695/
https://ncbi.nlm.nih.gov/pubmed/31308473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46763-y
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