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Vitamin D–regulated osteocytic sclerostin and BMP2 modulate uremic extraskeletal calcification
We induced chronic kidney disease (CKD) with adenine in WT mice, mice with osteocyte-specific deletion of Cyp27b1, encoding the 25-hydroxyvitamin D 1(OH)ase [Oct-1(OH)ase(–/–)], and mice with global deletion of Cyp27b1 [global-1α(OH)ase(–/–)]; we then compared extraskeletal calcification. After aden...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629247/ https://ncbi.nlm.nih.gov/pubmed/31292298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126467 |
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