High dietary salt–induced DC activation underlies microbial dysbiosis-associated hypertension

Excess dietary salt contributes to inflammation and hypertension via poorly understood mechanisms. Antigen-presenting cells including DCs play a key role in regulating intestinal immune homeostasis in part by surveying the gut epithelial surface for pathogens. Previously, we found that highly reacti...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Ferguson, Jane F., Aden, Luul A., Barbaro, Natalia R., Van Beusecum, Justin P., Xiao, Liang, Simons, Alan J., Warden, Cassandra, Pasic, Lejla, Himmel, Lauren E., Washington, Mary K., Revetta, Frank L., Zhao, Shilin, Kumaresan, Shivani, Scholz, Matthew B., Tang, Zhengzheng, Chen, Guanhua, Reilly, Muredach P., Kirabo, Annet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629246/
https://ncbi.nlm.nih.gov/pubmed/31162138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126241
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