High dietary salt–induced DC activation underlies microbial dysbiosis-associated hypertension

Excess dietary salt contributes to inflammation and hypertension via poorly understood mechanisms. Antigen-presenting cells including DCs play a key role in regulating intestinal immune homeostasis in part by surveying the gut epithelial surface for pathogens. Previously, we found that highly reacti...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Ferguson, Jane F., Aden, Luul A., Barbaro, Natalia R., Van Beusecum, Justin P., Xiao, Liang, Simons, Alan J., Warden, Cassandra, Pasic, Lejla, Himmel, Lauren E., Washington, Mary K., Revetta, Frank L., Zhao, Shilin, Kumaresan, Shivani, Scholz, Matthew B., Tang, Zhengzheng, Chen, Guanhua, Reilly, Muredach P., Kirabo, Annet
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629246/
https://ncbi.nlm.nih.gov/pubmed/31162138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126241
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