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High dietary salt–induced DC activation underlies microbial dysbiosis-associated hypertension

Excess dietary salt contributes to inflammation and hypertension via poorly understood mechanisms. Antigen-presenting cells including DCs play a key role in regulating intestinal immune homeostasis in part by surveying the gut epithelial surface for pathogens. Previously, we found that highly reacti...

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Detalles Bibliográficos
Publicado en:JCI Insight
Main Authors: Ferguson, Jane F., Aden, Luul A., Barbaro, Natalia R., Van Beusecum, Justin P., Xiao, Liang, Simons, Alan J., Warden, Cassandra, Pasic, Lejla, Himmel, Lauren E., Washington, Mary K., Revetta, Frank L., Zhao, Shilin, Kumaresan, Shivani, Scholz, Matthew B., Tang, Zhengzheng, Chen, Guanhua, Reilly, Muredach P., Kirabo, Annet
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629246/
https://ncbi.nlm.nih.gov/pubmed/31162138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126241
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