Clones of infected cells arise early in HIV-infected individuals

In HIV-infected individuals on long-term antiretroviral therapy (ART), more than 40% of the infected cells are in clones. Although most HIV proviruses present in individuals on long-term ART are defective, including those in clonally expanded cells, there is increasing evidence that clones carrying...

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Vydáno v:JCI Insight
Hlavní autoři: Coffin, John M., Wells, David W., Zerbato, Jennifer M., Kuruc, Joann D., Guo, Shuang, Luke, Brian T., Eron, Joseph J., Bale, Michael, Spindler, Jonathan, Simonetti, Francesco R., Hill, Shawn, Kearney, Mary F., Maldarelli, Frank, Wu, Xiaolin, Mellors, John W., Hughes, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629130/
https://ncbi.nlm.nih.gov/pubmed/31217357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.128432
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