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The combination of loss of glyoxalase1 and obesity results in hyperglycemia
The increased formation of methylglyoxal (MG) under hyperglycemia is associated with the development of microvascular complications in patients with diabetes mellitus; however, the effects of elevated MG levels in vivo are poorly understood. In zebrafish, a transient knockdown of glyoxalase 1, the m...
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| Publié dans: | JCI Insight |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6629122/ https://ncbi.nlm.nih.gov/pubmed/31217350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126154 |
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