The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology

Sepsis remains one of the leading causes of death in intensive care units. Although sepsis is caused by a viral, fungal or bacterial infection, it is the dysregulated generalized host response that ultimately leads to severe dysfunction of multiple organs and death. The concomitant profound metaboli...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Schmoch, Thomas, Uhle, Florian, Siegler, Benedikt H., Fleming, Thomas, Morgenstern, Jakob, Nawroth, Peter P., Weigand, Markus A., Brenner, Thorsten
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372669/
https://ncbi.nlm.nih.gov/pubmed/28304355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18030657
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