The combination of loss of glyoxalase1 and obesity results in hyperglycemia

The increased formation of methylglyoxal (MG) under hyperglycemia is associated with the development of microvascular complications in patients with diabetes mellitus; however, the effects of elevated MG levels in vivo are poorly understood. In zebrafish, a transient knockdown of glyoxalase 1, the m...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Lodd, Elisabeth, Wiggenhauser, Lucas M., Morgenstern, Jakob, Fleming, Thomas H., Poschet, Gernot, Büttner, Michael, Tabler, Christoph T., Wohlfart, David P., Nawroth, Peter P., Kroll, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629122/
https://ncbi.nlm.nih.gov/pubmed/31217350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126154
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