Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production

Engulfment and cell motility protein 1 (ELMO1) is part of a guanine nucleotide exchange factor for Ras-related C3 botulinum toxin substrate (Rac), and ELMO1 polymorphisms were identified to be associated with diabetic nephropathy in genome-wide association studies. We generated a set of Akita Ins2(C...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Kakoki, Masao, Bahnson, Edward M., Hagaman, John R., Siletzky, Robin M., Grant, Ruriko, Kayashima, Yukako, Li, Feng, Lee, Esther Y., Sun, Michelle T., Taylor, Joan M., Rice, Jessica C., Almeida, Michael F., Bahr, Ben A., Jennette, J. Charles, Smithies, Oliver, Maeda-Smithies, Nobuyo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629098/
https://ncbi.nlm.nih.gov/pubmed/31217360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127660
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