Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production

Engulfment and cell motility protein 1 (ELMO1) is part of a guanine nucleotide exchange factor for Ras-related C3 botulinum toxin substrate (Rac), and ELMO1 polymorphisms were identified to be associated with diabetic nephropathy in genome-wide association studies. We generated a set of Akita Ins2(C...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Kakoki, Masao, Bahnson, Edward M., Hagaman, John R., Siletzky, Robin M., Grant, Ruriko, Kayashima, Yukako, Li, Feng, Lee, Esther Y., Sun, Michelle T., Taylor, Joan M., Rice, Jessica C., Almeida, Michael F., Bahr, Ben A., Jennette, J. Charles, Smithies, Oliver, Maeda-Smithies, Nobuyo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629098/
https://ncbi.nlm.nih.gov/pubmed/31217360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127660
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