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Engulfment and cell motility protein 1 potentiates diabetic cardiomyopathy via Rac-dependent and Rac-independent ROS production

Engulfment and cell motility protein 1 (ELMO1) is part of a guanine nucleotide exchange factor for Ras-related C3 botulinum toxin substrate (Rac), and ELMO1 polymorphisms were identified to be associated with diabetic nephropathy in genome-wide association studies. We generated a set of Akita Ins2(C...

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書誌詳細
出版年:JCI Insight
主要な著者: Kakoki, Masao, Bahnson, Edward M., Hagaman, John R., Siletzky, Robin M., Grant, Ruriko, Kayashima, Yukako, Li, Feng, Lee, Esther Y., Sun, Michelle T., Taylor, Joan M., Rice, Jessica C., Almeida, Michael F., Bahr, Ben A., Jennette, J. Charles, Smithies, Oliver, Maeda-Smithies, Nobuyo
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6629098/
https://ncbi.nlm.nih.gov/pubmed/31217360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127660
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