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Recent advances in CAR T-cell toxicity: Mechanisms, manifestations and management

Chimeric antigen receptor (CAR) T-cell therapy is an effective new treatment for hematologic malignancies. Two CAR T-cell products are now approved for clinical use by the U.S. FDA: tisagenlecleucel for pediatric acute lymphoblastic leukemia (ALL) and adult diffuse large B-cell lymphoma subtypes (DL...

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Detalles Bibliográficos
Publicado en:Blood Rev
Autores principales: Brudno, Jennifer N., Kochenderfer, James N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628697/
https://ncbi.nlm.nih.gov/pubmed/30528964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2018.11.002
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